In vitro effectiveness of linezolid in brucellosis

نویسندگان

  • Hakan Sezgin Sayiner
  • Sadik Akgun
چکیده

Antibiotic sensitivities for Linezolid of 20 strains that reported as Brucella melitensis in blood cultures between 2014 and 2016 were evaluated by disc diffusion and E-test methods. According to the disc diffusion method results, 20 Brucella melitensis strains had ≥ 25 mm of antibiotic sensitivity zones. Etest measurements revealed that MIC values were between 1.5 and 6 μg. Linezolid can be an alternative when the treatment of Brucellosis prolongs and becomes difficult due to recurrences and relapses, or when it becomes complicated in cases like spondylodiscitis or neurobrucellosis.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Novel Linezolid like Analogues: Synthesis, Characterization and Biological Evaluation

The synthesis of 4-(substituted benzylidene)-2-(pyrazin-2-yl) oxazol-5(4H)-one was achieved in two steps, In first step, pyrazine-2-carboxamide  dissolved in EtOH, 10% KOH solution with ClCH2COOH produced compound 2-(pyrazine-2-carboxamido) acetic acid (II) and in second step, compound (II) in (CH3CO)2O with aromatic aldehyde, and catalyst potassium ace...

متن کامل

بررسی میکروبیولوژیک و حساسیت ضد میکروبی در موارد کشت مثبت بیماران مبتلا به تب مالت با سرولوژی مثبت

Background and purpose: Brucellosis is a zoonotic disease with worldwide distribution that is endemic in Iran. Worldwide, brucellosis remains a major cause of morbidity in humans and domesticated animals. The disease has a wide spectrum of clinical manifestation and can affect a variety of organs and systems. This study focused on blood culture of serologic diagnosed brucellosis and antimicro...

متن کامل

بررسی هزینه اثربخشی واکسیناسیون دام برعلیه بروسلوز در استان آذربایجان‌غربی

 Received: 13 January, 2009 Accepted: 4 Feb, 2009  Abstract   Background & Aims : Brucellosis is a widespread, economically devastating and highly infectious zoonosis. Mass immunization has become a favorite strategy to control of disease .in, this study, we tried to estimate marginal effectiveness of livestock immunization program in West-Azerbayjan province.   Materials &Methods : Epidemiolog...

متن کامل

Study on the linezolid prescription according to the approval of indication in a University Hospital

Indications for linezolid use are nosocomial or community-acquired pneumonia and skin infections or soft tissue infection caused by gram-positive microorganisms, but new recommendations may emerge. It is important to balance benefits with risks because severe adverse events have been described in patients taking linezolid treatment. Accordingly, we evaluated the suitability of linezolid prescri...

متن کامل

Effectiveness of Educational Intervention based on Protection Motivation Theory to Promotion of Preventive Behaviors from Brucellosis among Ranchers of Farmer

Aims: Brucellosis is one of the most important public health problems in developing countries, especially in rural areas closely related to animals. This study determines the effectiveness of an educational intervention based on Protection Motivation Theory on promoting preventive behaviors from brucellosis between the farmerchr('39')s ranchers in the comprehensive rural health center. Materia...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2017